Search on: MACROPHAGE-ACTIVATING FACTORS 
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Descriptor English:   Macrophage-Activating Factors 
Descriptor Spanish:   Factores Activadores de Macrófagos 
Descriptor Portuguese:   Fatores Ativadores de Macrófagos 
Tree Number:   D12.644.276.374.480.615
D12.776.467.374.480.615
D23.529.374.480.615
Definition English:   Factors secreted by stimulated lymphocytes that prime macrophages to become nonspecifically cytotoxic to tumors. They also modulate the expression of macrophage cell surface Ia antigens. One MAF is INTERFERON-GAMMA. Other factors antigenically distinct from IFN-gamma have also been identified. 
Indexing Annotation English:   a lymphokine; /biosyn /drug eff /physiol /ultrastruct permitted; DF: MAF
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   29033 
Unique Identifier:   D016215 

Occurrence in VHL:
 

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